Three New Abietane-Type Diterpenoids from Callicarpa macrophylla Vahl.

نویسندگان

  • Zhen-Hui Wang
  • Chao Niu
  • De-Jun Zhou
  • Ji-Chuan Kong
  • Wen-Kui Zhang
چکیده

Three new abietane-type diterpenoids, named callicapoic acid M3 (1), callicapoic acid M4 (2) and callicapoic acid M5 (3), were isolated from the Callicarpa macrophylla Vahl. Their structures were established by spectroscopic techniques (IR, UV, MS, 1D and 2D NMR). All the isolated three compounds were evaluated for inhibitory activity on NO production in LPS-activated RAW 264.7 macrophage cells by using MTT assays. Compounds 1, 2 and 3 showed potent inhibitory activity, with inhibition rates of 34.47-40.13%.

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عنوان ژورنال:
  • Molecules

دوره 22 5  شماره 

صفحات  -

تاریخ انتشار 2017